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AFM: MXene hydrogel skin sensor for intelligent human-machine interface and photothermal therapy

2023-12-13 10:25:17
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        Recently, the team of academician Zhang Liqun and professor Wan Pengbo from Beijing University of Chemical Technology skillfully introduced MXene nanosheet network into the hydrogel network containing low melting point agarose and polyvinyl alcohol, and easily prepared flexible multi-functional MXene hydrogel skin sensor.? It has high sensitivity, a wide sensing range (up to 350% strain), and reliable reproducibility for achieving ultra sensitive human-machine interfaces. It shows excellent anti swelling ability of hydrogel to avoid further expansion of wound due to excessive swelling and reliable wound treatment. In addition, it also has good biocompatibility and strong photothermal performance, which can achieve intelligent photothermal therapy and healthcare monitoring. At the same time, it can trigger the sensor to soften and decompose under long-term near-infrared light irradiation to transform the temperature sensitive low melting point agar into a sol state and partially dissociate in the hydrogel to release the loaded drug. Wound healing is required according to the collaborative sterilization and efficient promotion.

Highlights of this article

1. The flexible photothermal anti swelling hydrogel was prepared with MXene material.

2. Hydrogel has good biocompatibility and can be used as skin sensor.

3. Hydrogel combined with near-infrared light can be used for photothermal treatment to treat skin diseases.

4. Sensors can detect weak skin signals and achieve human-machine interaction.

5. Multi mode integration of photothermal therapy and biological signal detection has been achieved.

6. The performance of the hydrogel sensor is stable, comfortable to wear, and does not irritate the skin after long-term use.

7. Innovative research design and preparation of novel implantable soft sensing materials.

8. The multifunctionality of soft sensors has been achieved, demonstrating the potential application of human-computer interaction.

9. Provides new ideas for the development of next-generation implantable and biodegradable medical electronic products.

10. The research has a certain degree of innovation and can be applied in the field of clinical medicine.

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Figure 1. Preparation of flexible multi-functional conductive MXene hydrogel and its functional schematic diagram

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Figure 2 Scanning electron microscopy (SEM) images

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Figure 3. MXene hydrogel skin sensor monitoring human movement

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Figure 4 Monitoring of human electrophysiological signals with MXene hydrogel epidermal sensor

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Figure 5. Application of MXene Hydrogel Skin Sensor in Intelligent Human Machine Interface

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Figure 6. Application of MXene Hydrogel Skin Sensor in Intelligent Human Machine Interface

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Figure 7. Photothermal performance of MXene hydrogel skin sensor

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Figure 8. MXene hydrogel epidermal sensor releases antibiotics on demand

summary

        The author has prepared a multi-functional MXene hydrogel skin sensor through a simple method. The sensor can not only be used for intelligent human-computer interface, but also has ultra sensitive medical care sensing performance and timely treatment ability, which is expected to change the personalized medical care pattern of human-computer interaction and intelligent diagnosis and treatment.

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